| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB16027.1 | mat | Halru_1415 | Halru_1416 | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | Archaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | 0.840 |
| AGB16027.1 | thiI | Halru_1415 | Halru_1417 | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.646 |
| AGB16030.1 | mat | Halru_1418 | Halru_1416 | Hypothetical protein. | Archaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | 0.724 |
| AGB16030.1 | thiI | Halru_1418 | Halru_1417 | Hypothetical protein. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.802 |
| AGB16430.1 | thiI | Halru_1831 | Halru_1417 | PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.677 |
| AGB16430.1 | trm1 | Halru_1831 | Halru_2684 | PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.637 |
| AGB16430.1 | truA | Halru_1831 | Halru_0099 | PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.592 |
| AGB16430.1 | truB | Halru_1831 | Halru_2068 | PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.723 |
| AGB17331.1 | thiI | Halru_2756 | Halru_1417 | PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.565 |
| mat | AGB16027.1 | Halru_1416 | Halru_1415 | Archaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | 0.840 |
| mat | AGB16030.1 | Halru_1416 | Halru_1418 | Archaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | Hypothetical protein. | 0.724 |
| mat | thiI | Halru_1416 | Halru_1417 | Archaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.829 |
| pus10 | thiI | Halru_0077 | Halru_1417 | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.540 |
| pus10 | tiaS | Halru_0077 | Halru_2032 | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.464 |
| pus10 | trm1 | Halru_0077 | Halru_2684 | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.727 |
| pus10 | truA | Halru_0077 | Halru_0099 | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.717 |
| pus10 | truB | Halru_0077 | Halru_2068 | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.587 |
| thiI | AGB16027.1 | Halru_1417 | Halru_1415 | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | 0.646 |
| thiI | AGB16030.1 | Halru_1417 | Halru_1418 | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | Hypothetical protein. | 0.802 |
| thiI | AGB16430.1 | Halru_1417 | Halru_1831 | Thiamine biosynthesis ATP pyrophosphatase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.677 |
