| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB16040.1 | AGB16041.1 | Halru_1428 | Halru_1429 | PFAM: Membrane protein of unknown function DUF63. | PFAM: Inositol monophosphatase family. | 0.815 |
| AGB16041.1 | AGB16040.1 | Halru_1429 | Halru_1428 | PFAM: Inositol monophosphatase family. | PFAM: Membrane protein of unknown function DUF63. | 0.815 |
| AGB16041.1 | gap | Halru_1429 | Halru_0450 | PFAM: Inositol monophosphatase family. | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | 0.686 |
| AGB16041.1 | hisA | Halru_1429 | Halru_3134 | PFAM: Inositol monophosphatase family. | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.583 |
| AGB16041.1 | hisF | Halru_1429 | Halru_1344 | PFAM: Inositol monophosphatase family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.527 |
| AGB16041.1 | nadK-2 | Halru_1429 | Halru_1658 | PFAM: Inositol monophosphatase family. | Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.921 |
| AGB16041.1 | nusA | Halru_1429 | Halru_0468 | PFAM: Inositol monophosphatase family. | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. | 0.708 |
| AGB16041.1 | prs | Halru_1429 | Halru_3160 | PFAM: Inositol monophosphatase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.633 |
| AGB16041.1 | rpoD | Halru_1429 | Halru_1750 | PFAM: Inositol monophosphatase family. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.506 |
| AGB16041.1 | rpoK | Halru_1429 | Halru_1744 | PFAM: Inositol monophosphatase family. | DNA-directed RNA polymerase, subunit K/omega; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.667 |
| AGB16041.1 | spt5 | Halru_1429 | Halru_2288 | PFAM: Inositol monophosphatase family. | Ribosomal protein L24p/L26e, archaeal; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.582 |
| gap | AGB16041.1 | Halru_0450 | Halru_1429 | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | PFAM: Inositol monophosphatase family. | 0.686 |
| gap | nadK-2 | Halru_0450 | Halru_1658 | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.884 |
| gap | prs | Halru_0450 | Halru_3160 | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.611 |
| gap | rpoD | Halru_0450 | Halru_1750 | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.559 |
| gap | spt5 | Halru_0450 | Halru_2288 | Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II. | Ribosomal protein L24p/L26e, archaeal; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.444 |
| hisA | AGB16041.1 | Halru_3134 | Halru_1429 | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | PFAM: Inositol monophosphatase family. | 0.583 |
| hisA | hisF | Halru_3134 | Halru_1344 | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.996 |
| hisA | nadK-2 | Halru_3134 | Halru_1658 | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.662 |
| hisA | prs | Halru_3134 | Halru_3160 | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.507 |