Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB16057.1Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function. (176 aa)    
Predicted Functional Partners:
AGB14660.1
PFAM: Uncharacterized protein conserved in archaea (DUF2073).
  
     0.737
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.725
AGB17003.1
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase; PFAM: ACT domain.
  
     0.710
AGB15684.1
Putative transcriptional regulator; PFAM: MarR family.
  
     0.684
secE
Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.671
AGB16059.1
PFAM: Arginase family; TIGRFAM: arginase; Belongs to the arginase family.
       0.667
AGB15382.1
Putative metal-binding protein; PFAM: Uncharacterised protein family UPF0058.
  
     0.658
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
     0.655
AGB15164.1
PFAM: Protein of unknown function (DUF460).
  
     0.654
AGB16320.1
TIGRFAM: TIM-barrel protein, putative.
  
     0.633
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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