Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB16063.1Helicase family protein with metal-binding cysteine cluster; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase. (906 aa)    
Predicted Functional Partners:
AGB16064.1
Hypothetical protein; TIGRFAM: RecB family nuclease, putative, TM0106 family.
       0.903
AGB16681.1
Kef-type K+ transport system, membrane component; PFAM: Sodium/hydrogen exchanger family.
   
    0.846
AGB17597.1
Putative permease, DMT superfamily; PFAM: EamA-like transporter family.
   
    0.571
AGB16167.1
Putative exonuclease.
 
    0.563
purD
Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family.
       0.525
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.498
AGB16066.1
PFAM: Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
       0.498
dbh
nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
  
 
   0.469
AGB15318.1
DNA polymerase elongation subunit (family B); PFAM: DNA polymerase family B.
  
 
   0.452
AGB14969.1
Putative ATPase, Rnase L inhibitor (RLI) like protein; PFAM: ABC transporter; Possible metal-binding domain in RNase L inhibitor, RLI.
       0.416
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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