Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB16067.1Hypothetical protein; PFAM: PhoU domain; TrkA-C domain. (402 aa)    
Predicted Functional Partners:
AGB16069.1
PFAM: Divalent cation transporter.
 
     0.833
AGB16068.1
PFAM: Divalent cation transporter.
 
     0.768
AGB16662.1
PFAM: Integral membrane protein DUF106.
  
     0.631
secE
Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.606
AGB14661.1
PFAM: Zn-ribbon containing protein (DUF2072).
  
     0.605
rpl39e
PFAM: Ribosomal L39 protein; Belongs to the eukaryotic ribosomal protein eL39 family.
  
     0.567
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.548
AGB16066.1
PFAM: Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
       0.548
purC
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
  
     0.520
AGB14947.1
Zn-dependent carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
   
    0.512
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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