Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB16182.1Putative phosphoesterase, ICC. (287 aa)    
Predicted Functional Partners:
AGB16180.1
Single-stranded DNA-binding protein.
 
   
 0.990
AGB16181.1
Hypothetical protein.
 
   
 0.943
AGB16183.1
PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase.
 
    0.916
AGB17134.1
Single-stranded DNA-binding protein.
 
   
 0.729
AGB16179.1
2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal.
       0.720
AGB17135.1
Hypothetical protein.
  
   
 0.670
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
   
 0.661
AGB16689.1
PFAM: Uncharacterized protein conserved in archaea (DUF2240).
 
     0.636
AGB17359.1
Single-stranded DNA-binding protein; PFAM: OB-fold nucleic acid binding domain.
 
   
 0.634
AGB17017.1
ATP-grasp superfamily enzyme; PFAM: PAC2 family; TIGRFAM: TIGR00161 family protein.
  
     0.590
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.