| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14958.1 | AGB16501.1 | Halru_0314 | Halru_1903 | ATPase (PilT family); PFAM: KH domain; Type II/IV secretion system protein; PIN domain. | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | 0.481 |
| AGB14958.1 | tfe | Halru_0314 | Halru_1280 | ATPase (PilT family); PFAM: KH domain; Type II/IV secretion system protein; PIN domain. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.609 |
| AGB15775.1 | AGB16501.1 | Halru_1158 | Halru_1903 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | 0.505 |
| AGB15775.1 | fau-1 | Halru_1158 | Halru_0266 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Protein of unknown function (DUF402); Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.606 |
| AGB15775.1 | pfdB | Halru_1158 | Halru_1167 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Prefoldin, beta subunit, archaeal; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.528 |
| AGB15775.1 | tfe | Halru_1158 | Halru_1280 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.539 |
| AGB16027.1 | AGB16501.1 | Halru_1415 | Halru_1903 | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | 0.482 |
| AGB16027.1 | gch3 | Halru_1415 | Halru_1555 | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | Hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. | 0.826 |
| AGB16500.1 | AGB16501.1 | Halru_1902 | Halru_1903 | Hypothetical protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase. | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | 0.605 |
| AGB16500.1 | AGB16502.1 | Halru_1902 | Halru_1904 | Hypothetical protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase. | PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter. | 0.486 |
| AGB16500.1 | AGB16503.1 | Halru_1902 | Halru_1905 | Hypothetical protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase. | Putative endoIII-related endonuclease; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif. | 0.419 |
| AGB16501.1 | AGB14958.1 | Halru_1903 | Halru_0314 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | ATPase (PilT family); PFAM: KH domain; Type II/IV secretion system protein; PIN domain. | 0.481 |
| AGB16501.1 | AGB15775.1 | Halru_1903 | Halru_1158 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | 0.505 |
| AGB16501.1 | AGB16027.1 | Halru_1903 | Halru_1415 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative; manually curated. | 0.482 |
| AGB16501.1 | AGB16500.1 | Halru_1903 | Halru_1902 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Hypothetical protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase. | 0.605 |
| AGB16501.1 | AGB16502.1 | Halru_1903 | Halru_1904 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter. | 0.718 |
| AGB16501.1 | AGB16503.1 | Halru_1903 | Halru_1905 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Putative endoIII-related endonuclease; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif. | 0.597 |
| AGB16501.1 | fau-1 | Halru_1903 | Halru_0266 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Protein of unknown function (DUF402); Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.587 |
| AGB16501.1 | gch3 | Halru_1903 | Halru_1555 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. | 0.528 |
| AGB16501.1 | pfdB | Halru_1903 | Halru_1167 | Hypothetical protein; PFAM: Domain of unknown function (DUF371). | Prefoldin, beta subunit, archaeal; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.566 |