| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14795.1 | AGB15892.1 | Halru_0143 | Halru_1278 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.554 |
| AGB14795.1 | AGB16578.1 | Halru_0143 | Halru_1983 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.708 |
| AGB14795.1 | AGB16590.1 | Halru_0143 | Halru_1996 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | 0.619 |
| AGB14795.1 | dphB | Halru_0143 | Halru_1978 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.549 |
| AGB14795.1 | rlmE | Halru_0143 | Halru_2858 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.572 |
| AGB14795.1 | rpoD | Halru_0143 | Halru_1750 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.913 |
| AGB14795.1 | truD | Halru_0143 | Halru_1162 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | tRNA pseudouridine synthase, TruD family; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.700 |
| AGB15892.1 | AGB14795.1 | Halru_1278 | Halru_0143 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.554 |
| AGB15892.1 | AGB16578.1 | Halru_1278 | Halru_1983 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.621 |
| AGB15892.1 | ef1b | Halru_1278 | Halru_1389 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.640 |
| AGB16577.1 | AGB16578.1 | Halru_1982 | Halru_1983 | Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase; PFAM: Rieske [2Fe-2S] domain. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.608 |
| AGB16578.1 | AGB14795.1 | Halru_1983 | Halru_0143 | Putative methyltransferase; PFAM: Met-10+ like-protein. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.708 |
| AGB16578.1 | AGB15892.1 | Halru_1983 | Halru_1278 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.621 |
| AGB16578.1 | AGB16577.1 | Halru_1983 | Halru_1982 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase; PFAM: Rieske [2Fe-2S] domain. | 0.608 |
| AGB16578.1 | AGB16590.1 | Halru_1983 | Halru_1996 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | 0.743 |
| AGB16578.1 | dphB | Halru_1983 | Halru_1978 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.775 |
| AGB16578.1 | ef1b | Halru_1983 | Halru_1389 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.679 |
| AGB16578.1 | rlmE | Halru_1983 | Halru_2858 | Putative methyltransferase; PFAM: Met-10+ like-protein. | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.611 |
| AGB16578.1 | rpoD | Halru_1983 | Halru_1750 | Putative methyltransferase; PFAM: Met-10+ like-protein. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.626 |
| AGB16578.1 | taw1 | Halru_1983 | Halru_0983 | Putative methyltransferase; PFAM: Met-10+ like-protein. | Wyosine biosynthesis protein TYW1; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.610 |