| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14743.1 | AGB15892.1 | Halru_0091 | Halru_1278 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.534 |
| AGB14743.1 | AGB16879.1 | Halru_0091 | Halru_2294 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain. | 0.425 |
| AGB14743.1 | AGB17076.1 | Halru_0091 | Halru_2494 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.700 |
| AGB14743.1 | AGB17125.1 | Halru_0091 | Halru_2544 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.537 |
| AGB14743.1 | AGB17668.1 | Halru_0091 | Halru_3102 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: CBS domain. | 0.443 |
| AGB14743.1 | mptE | Halru_0091 | Halru_1372 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.557 |
| AGB14743.1 | ribK | Halru_0091 | Halru_2255 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.537 |
| AGB14743.1 | tiaS | Halru_0091 | Halru_2032 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.633 |
| AGB15892.1 | AGB14743.1 | Halru_1278 | Halru_0091 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | 0.534 |
| AGB15892.1 | AGB16879.1 | Halru_1278 | Halru_2294 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain. | 0.746 |
| AGB15892.1 | AGB17076.1 | Halru_1278 | Halru_2494 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.777 |
| AGB15892.1 | AGB17125.1 | Halru_1278 | Halru_2544 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.630 |
| AGB15892.1 | ef1b | Halru_1278 | Halru_1389 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.640 |
| AGB15892.1 | mptE | Halru_1278 | Halru_1372 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.476 |
| AGB15892.1 | ribK | Halru_1278 | Halru_2255 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.640 |
| AGB15892.1 | tiaS | Halru_1278 | Halru_2032 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.710 |
| AGB16625.1 | AGB17076.1 | Halru_2031 | Halru_2494 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.536 |
| AGB16625.1 | AGB17125.1 | Halru_2031 | Halru_2544 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.523 |
| AGB16625.1 | AGB17668.1 | Halru_2031 | Halru_3102 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: CBS domain. | 0.525 |
| AGB16625.1 | mptE | Halru_2031 | Halru_1372 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.609 |