| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15449.1 | carS | Halru_0823 | Halru_2249 | Phosphatidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.911 |
| AGB15549.1 | AGB15860.1 | Halru_0929 | Halru_1246 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | 0.954 |
| AGB15549.1 | AGB17056.1 | Halru_0929 | Halru_2474 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranyl reductase family protein; PFAM: Tryptophan halogenase; FAD binding domain; TIGRFAM: geranylgeranyl reductase family. | 0.955 |
| AGB15549.1 | carS | Halru_0929 | Halru_2249 | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.961 |
| AGB15860.1 | AGB15549.1 | Halru_1246 | Halru_0929 | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.954 |
| AGB15860.1 | AGB17056.1 | Halru_1246 | Halru_2474 | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | Geranylgeranyl reductase family protein; PFAM: Tryptophan halogenase; FAD binding domain; TIGRFAM: geranylgeranyl reductase family. | 0.930 |
| AGB15860.1 | carS | Halru_1246 | Halru_2249 | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.953 |
| AGB16836.1 | AGB16837.1 | Halru_2250 | Halru_2251 | PFAM: Proline dehydrogenase. | PFAM: Protein of unknown function (DUF502). | 0.795 |
| AGB16836.1 | carS | Halru_2250 | Halru_2249 | PFAM: Proline dehydrogenase. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.773 |
| AGB16836.1 | pyrE | Halru_2250 | Halru_2248 | PFAM: Proline dehydrogenase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.402 |
| AGB16837.1 | AGB16836.1 | Halru_2251 | Halru_2250 | PFAM: Protein of unknown function (DUF502). | PFAM: Proline dehydrogenase. | 0.795 |
| AGB16837.1 | carS | Halru_2251 | Halru_2249 | PFAM: Protein of unknown function (DUF502). | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.709 |
| AGB17056.1 | AGB15549.1 | Halru_2474 | Halru_0929 | Geranylgeranyl reductase family protein; PFAM: Tryptophan halogenase; FAD binding domain; TIGRFAM: geranylgeranyl reductase family. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.955 |
| AGB17056.1 | AGB15860.1 | Halru_2474 | Halru_1246 | Geranylgeranyl reductase family protein; PFAM: Tryptophan halogenase; FAD binding domain; TIGRFAM: geranylgeranyl reductase family. | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | 0.930 |
| AGB17056.1 | carS | Halru_2474 | Halru_2249 | Geranylgeranyl reductase family protein; PFAM: Tryptophan halogenase; FAD binding domain; TIGRFAM: geranylgeranyl reductase family. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.954 |
| carS | AGB15449.1 | Halru_2249 | Halru_0823 | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Phosphatidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.911 |
| carS | AGB15549.1 | Halru_2249 | Halru_0929 | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.961 |
| carS | AGB15860.1 | Halru_2249 | Halru_1246 | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Flavin-dependent dehydrogenase; PFAM: Lycopene cyclase protein. | 0.953 |
| carS | AGB16836.1 | Halru_2249 | Halru_2250 | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Proline dehydrogenase. | 0.773 |
| carS | AGB16837.1 | Halru_2249 | Halru_2251 | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Protein of unknown function (DUF502). | 0.709 |