| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14916.1 | AGB16179.1 | Halru_0270 | Halru_1572 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 0.981 |
| AGB14916.1 | AGB16840.1 | Halru_0270 | Halru_2254 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.993 |
| AGB14916.1 | ribH | Halru_0270 | Halru_0808 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| AGB14916.1 | ribK | Halru_0270 | Halru_2255 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.900 |
| AGB16179.1 | AGB14916.1 | Halru_1572 | Halru_0270 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.981 |
| AGB16179.1 | AGB16840.1 | Halru_1572 | Halru_2254 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.948 |
| AGB16179.1 | ribH | Halru_1572 | Halru_0808 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.951 |
| AGB16840.1 | AGB14916.1 | Halru_2254 | Halru_0270 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.993 |
| AGB16840.1 | AGB16179.1 | Halru_2254 | Halru_1572 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 0.948 |
| AGB16840.1 | AGB17189.1 | Halru_2254 | Halru_2610 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. | 0.594 |
| AGB16840.1 | argS | Halru_2254 | Halru_2567 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.690 |
| AGB16840.1 | ilvE | Halru_2254 | Halru_2252 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.542 |
| AGB16840.1 | lysY | Halru_2254 | Halru_0400 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | N-acetyl-gamma-glutamyl-phosphate reductase, common form; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.585 |
| AGB16840.1 | ribH | Halru_2254 | Halru_0808 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
| AGB16840.1 | ribK | Halru_2254 | Halru_2255 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.911 |
| AGB16840.1 | rps2 | Halru_2254 | Halru_1742 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family. | 0.618 |
| AGB16840.1 | taw1 | Halru_2254 | Halru_0983 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Wyosine biosynthesis protein TYW1; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.555 |
| AGB17189.1 | AGB16840.1 | Halru_2610 | Halru_2254 | PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.594 |
| AGB17189.1 | ilvE | Halru_2610 | Halru_2252 | PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.755 |
| AGB17189.1 | lysY | Halru_2610 | Halru_0400 | PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. | N-acetyl-gamma-glutamyl-phosphate reductase, common form; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.584 |