| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14916.1 | AGB16840.1 | Halru_0270 | Halru_2254 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.993 |
| AGB14916.1 | ribK | Halru_0270 | Halru_2255 | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.900 |
| AGB16691.1 | AGB16853.1 | Halru_2099 | Halru_2267 | Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain. | Hypothetical protein; Involved in DNA damage repair. | 0.633 |
| AGB16691.1 | priS | Halru_2099 | Halru_1764 | Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain. | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.573 |
| AGB16691.1 | ribK | Halru_2099 | Halru_2255 | Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.663 |
| AGB16691.1 | tiaS | Halru_2099 | Halru_2032 | Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.457 |
| AGB16840.1 | AGB14916.1 | Halru_2254 | Halru_0270 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.993 |
| AGB16840.1 | ribK | Halru_2254 | Halru_2255 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.911 |
| AGB16840.1 | ribL | Halru_2254 | Halru_0811 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.431 |
| AGB16853.1 | AGB16691.1 | Halru_2267 | Halru_2099 | Hypothetical protein; Involved in DNA damage repair. | Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain. | 0.633 |
| AGB16853.1 | dnaG | Halru_2267 | Halru_2191 | Hypothetical protein; Involved in DNA damage repair. | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.599 |
| AGB16853.1 | priS | Halru_2267 | Halru_1764 | Hypothetical protein; Involved in DNA damage repair. | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.430 |
| AGB16853.1 | ribK | Halru_2267 | Halru_2255 | Hypothetical protein; Involved in DNA damage repair. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.656 |
| AGB17076.1 | dnaG | Halru_2494 | Halru_2191 | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.555 |
| AGB17076.1 | priS | Halru_2494 | Halru_1764 | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | DNA primase, eukaryotic-type, small subunit, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extens [...] | 0.523 |
| AGB17076.1 | ribK | Halru_2494 | Halru_2255 | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.667 |
| AGB17076.1 | tiaS | Halru_2494 | Halru_2032 | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.731 |
| dnaG | AGB16853.1 | Halru_2191 | Halru_2267 | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Hypothetical protein; Involved in DNA damage repair. | 0.599 |
| dnaG | AGB17076.1 | Halru_2191 | Halru_2494 | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.555 |
| dnaG | eif2b | Halru_2191 | Halru_2349 | Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.562 |