Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB16878.1ADP-ribose pyrophosphatase; PFAM: NUDIX domain. (180 aa)    
Predicted Functional Partners:
rad25
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
  
  
 0.634
AGB17147.1
Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
       0.613
nadK-2
Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.609
AGB16184.1
PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein.
 
     0.510
pcn-2
DNA polymerase sliding clamp subunit; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
     
 0.503
AGB15449.1
Phosphatidylserine synthase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.490
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.482
AGB16676.1
PFAM: Catalase; DJ-1/PfpI family; Catalase-related immune-responsive.
     
 0.459
AGB17654.1
Single-stranded DNA-specific exonuclease; PFAM: DHHA1 domain; DHH family.
  
  
 0.439
AGB16205.1
PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2.
 
  
 0.425
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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