| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14743.1 | AGB15892.1 | Halru_0091 | Halru_1278 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.534 |
| AGB14743.1 | AGB17017.1 | Halru_0091 | Halru_2435 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | ATP-grasp superfamily enzyme; PFAM: PAC2 family; TIGRFAM: TIGR00161 family protein. | 0.429 |
| AGB14743.1 | AGB17076.1 | Halru_0091 | Halru_2494 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.700 |
| AGB14743.1 | AGB17654.1 | Halru_0091 | Halru_3088 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Single-stranded DNA-specific exonuclease; PFAM: DHHA1 domain; DHH family. | 0.438 |
| AGB14743.1 | nac | Halru_0091 | Halru_2496 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | alpha-NAC-related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.449 |
| AGB14743.1 | ribK | Halru_0091 | Halru_2255 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.537 |
| AGB14743.1 | tgtA | Halru_0091 | Halru_0675 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.405 |
| AGB14743.1 | tiaS | Halru_0091 | Halru_2032 | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.633 |
| AGB15892.1 | AGB14743.1 | Halru_1278 | Halru_0091 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | 0.534 |
| AGB15892.1 | AGB17017.1 | Halru_1278 | Halru_2435 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | ATP-grasp superfamily enzyme; PFAM: PAC2 family; TIGRFAM: TIGR00161 family protein. | 0.489 |
| AGB15892.1 | AGB17076.1 | Halru_1278 | Halru_2494 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.777 |
| AGB15892.1 | AGB17079.1 | Halru_1278 | Halru_2497 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | tRNA(1-methyladenosine) methyltransferase-like methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit. | 0.530 |
| AGB15892.1 | AGB17654.1 | Halru_1278 | Halru_3088 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Single-stranded DNA-specific exonuclease; PFAM: DHHA1 domain; DHH family. | 0.518 |
| AGB15892.1 | carS | Halru_1278 | Halru_2249 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.576 |
| AGB15892.1 | nac | Halru_1278 | Halru_2496 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | alpha-NAC-related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.727 |
| AGB15892.1 | ribK | Halru_1278 | Halru_2255 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.640 |
| AGB15892.1 | tgtA | Halru_1278 | Halru_0675 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.536 |
| AGB15892.1 | tiaS | Halru_1278 | Halru_2032 | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.710 |
| AGB17017.1 | AGB14743.1 | Halru_2435 | Halru_0091 | ATP-grasp superfamily enzyme; PFAM: PAC2 family; TIGRFAM: TIGR00161 family protein. | Putative nucleic acid-binding protein with PIN domain and Zn ribbon. | 0.429 |
| AGB17017.1 | AGB15892.1 | Halru_2435 | Halru_1278 | ATP-grasp superfamily enzyme; PFAM: PAC2 family; TIGRFAM: TIGR00161 family protein. | Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.489 |