Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB17187.1ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region. (646 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone.
 
 0.649
AGB14909.1
ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter.
   
0.645
AGB14706.1
Ankyrin repeat-containing protein; PFAM: Ankyrin repeat.
  
 0.584
AGB17361.1
Deacetylase, histone deacetylase/acetoin utilization protein; PFAM: Histone deacetylase domain.
  
 0.578
AGB15061.1
PFAM: ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.
 
 
 0.576
AGB14987.1
PFAM: Tetratricopeptide repeat.
  
 
 0.527
infB
Translation initiation factor aIF-2/yIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
 
 
 0.514
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
  0.512
pan-2
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
  0.501
AGB15316.1
Protein-tyrosine-phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
 
 
 
 0.495
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.