| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14795.1 | AGB16590.1 | Halru_0143 | Halru_1996 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | 0.619 |
| AGB14795.1 | AGB17337.1 | Halru_0143 | Halru_2762 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | NMD protein affecting ribosome stability and mRNA decay; PFAM: NMD3 family. | 0.836 |
| AGB14795.1 | AGB17338.1 | Halru_0143 | Halru_2763 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.595 |
| AGB14795.1 | dphB | Halru_0143 | Halru_1978 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.549 |
| AGB14795.1 | pus10 | Halru_0143 | Halru_0077 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. | 0.444 |
| AGB14795.1 | rlmE | Halru_0143 | Halru_2858 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.572 |
| AGB14795.1 | tiaS | Halru_0143 | Halru_2032 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.428 |
| AGB15771.1 | AGB17338.1 | Halru_1154 | Halru_2763 | Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.487 |
| AGB15771.1 | tiaS | Halru_1154 | Halru_2032 | Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.624 |
| AGB16590.1 | AGB14795.1 | Halru_1996 | Halru_0143 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.619 |
| AGB16590.1 | AGB17337.1 | Halru_1996 | Halru_2762 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | NMD protein affecting ribosome stability and mRNA decay; PFAM: NMD3 family. | 0.679 |
| AGB16590.1 | AGB17338.1 | Halru_1996 | Halru_2763 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.439 |
| AGB16590.1 | dphB | Halru_1996 | Halru_1978 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.607 |
| AGB16590.1 | rlmE | Halru_1996 | Halru_2858 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.470 |
| AGB16590.1 | taw1 | Halru_1996 | Halru_0983 | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | Wyosine biosynthesis protein TYW1; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.414 |
| AGB16732.1 | AGB17338.1 | Halru_2143 | Halru_2763 | Outer membrane lipoprotein-sorting protein. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.520 |
| AGB16732.1 | taw1 | Halru_2143 | Halru_0983 | Outer membrane lipoprotein-sorting protein. | Wyosine biosynthesis protein TYW1; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). | 0.407 |
| AGB17337.1 | AGB14795.1 | Halru_2762 | Halru_0143 | NMD protein affecting ribosome stability and mRNA decay; PFAM: NMD3 family. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.836 |
| AGB17337.1 | AGB16590.1 | Halru_2762 | Halru_1996 | NMD protein affecting ribosome stability and mRNA decay; PFAM: NMD3 family. | Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family. | 0.679 |
| AGB17337.1 | AGB17338.1 | Halru_2762 | Halru_2763 | NMD protein affecting ribosome stability and mRNA decay; PFAM: NMD3 family. | Putative methyltransferase; PFAM: Met-10+ like-protein. | 0.876 |