| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15151.1 | AGB17724.1 | Halru_0516 | Halru_3158 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | 0.921 |
| AGB15151.1 | pyrF | Halru_0516 | Halru_2078 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.910 |
| AGB15151.1 | pyrH | Halru_0516 | Halru_2780 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.911 |
| AGB15151.1 | surE | Halru_0516 | Halru_0850 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
| AGB15151.1 | upp | Halru_0516 | Halru_3125 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.913 |
| AGB17352.1 | lysS | Halru_2778 | Halru_2779 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.922 |
| AGB17352.1 | pyrG | Halru_2778 | Halru_0672 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.484 |
| AGB17352.1 | pyrH | Halru_2778 | Halru_2780 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.964 |
| AGB17352.1 | rps2 | Halru_2778 | Halru_1742 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family. | 0.690 |
| AGB17724.1 | AGB15151.1 | Halru_3158 | Halru_0516 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase. | 0.921 |
| AGB17724.1 | pyrF | Halru_3158 | Halru_2078 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.905 |
| AGB17724.1 | pyrH | Halru_3158 | Halru_2780 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| AGB17724.1 | surE | Halru_3158 | Halru_0850 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
| AGB17724.1 | upp | Halru_3158 | Halru_3125 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.905 |
| lysS | AGB17352.1 | Halru_2779 | Halru_2778 | PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | 0.922 |
| lysS | pyrH | Halru_2779 | Halru_2780 | PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.927 |
| ndk | pyrF | Halru_1728 | Halru_2078 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.404 |
| ndk | pyrG | Halru_1728 | Halru_0672 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.938 |
| ndk | pyrH | Halru_1728 | Halru_2780 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.940 |
| ndk | rps2 | Halru_1728 | Halru_1742 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family. | 0.981 |