Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB17360.1Histones H3 and H4; PFAM: Histone-like transcription factor (CBF/NF-Y) and archaeal histone. (143 aa)    
Predicted Functional Partners:
AGB17361.1
Deacetylase, histone deacetylase/acetoin utilization protein; PFAM: Histone deacetylase domain.
   
 
 0.956
AGB17359.1
Single-stranded DNA-binding protein; PFAM: OB-fold nucleic acid binding domain.
 
  
 0.893
rnp3
RNase P/RNase MRP subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.721
purO
IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
  
     0.667
AGB17339.1
DEAD_2 domain-containing protein; PFAM: DEAD_2.
  
  
  0.633
AGB15847.1
Putative RNA-binding protein, contains TRAM domain; PFAM: TRAM domain.
  
    0.626
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
   
 0.616
secE
Protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
    0.607
AGB16057.1
Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function.
  
     0.599
gch3
Hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
  
     0.586
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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