Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB17652.1PFAM: Uroporphyrinogen-III synthase HemD. (261 aa)    
Predicted Functional Partners:
AGB17651.1
PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
 
 0.999
AGB17645.1
PFAM: Delta-aminolevulinic acid dehydratase.
 
 
 0.962
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.941
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.853
hemL
PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
 
  
 0.790
AGB15585.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
    0.721
AGB16526.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
  
    0.684
AGB17654.1
Single-stranded DNA-specific exonuclease; PFAM: DHHA1 domain; DHH family.
 
     0.634
AGB17650.1
Hypothetical protein.
       0.563
AGB17350.1
Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase.
 
   
 0.562
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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