Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
polCDNA polymerase type II, large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1208 aa)    
Predicted Functional Partners:
polB
Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
   
 0.948
AGB17661.1
Putative DNA-binding protein with PD1-like DNA-binding motif; PFAM: Domain of unknown function (DUF296).
       0.911
AGB14656.1
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
 
   
 0.789
nac
alpha-NAC-related protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.733
AGB15685.1
PFAM: PAC2 family; TIGRFAM: TIGR00162 family protein.
  
     0.727
AGB17654.1
Single-stranded DNA-specific exonuclease; PFAM: DHHA1 domain; DHH family.
 
   
 0.725
AGB15322.1
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
 
   
 0.708
spt5
Ribosomal protein L24p/L26e, archaeal; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.692
AGB15994.1
Putative RNA-binding protein; PFAM: Protein of unknown function, DUF655.
  
     0.678
dnaG
Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.675
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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