close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB30052.1PFAM: Protein of unknown function (DUF460). (658 aa)    
Predicted Functional Partners:
AGB31475.1
PFAM: Uncharacterized protein conserved in archaea (DUF2150).
  
     0.713
AGB32784.1
Putative membrane protein; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: exosortase/archaeosortase family protein; archaeosortase A, PGF-CTERM-specific.
 
     0.707
AGB33638.1
PFAM: Uncharacterized protein conserved in archaea (DUF2073).
  
     0.696
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
     0.691
AGB30919.1
Putative membrane protein, required for N-linked glycosylation; PFAM: Oligosaccharyl transferase STT3 subunit; TIGRFAM: oligosaccharyl transferase, archaeosortase system-associated.
  
     0.688
AGB31109.1
PFAM: Protein of unknown function (DUF555); Belongs to the UPF0212 family.
  
     0.687
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.685
AGB32176.1
Hypothetical protein.
  
     0.682
AGB33157.1
Putative Fe-S oxidoreductase; PFAM: Uncharacterised protein family (UPF0153).
  
     0.682
AGB32381.1
PFAM: Protein of unknown function (DUF555); Belongs to the UPF0212 family.
  
     0.674
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
Server load: low (24%) [HD]