| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30119.1 | AGB30120.1 | Natpe_0177 | Natpe_0178 | PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC. | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | 0.569 |
| AGB30119.1 | AGB30121.1 | Natpe_0177 | Natpe_0179 | PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.440 |
| AGB30120.1 | AGB30119.1 | Natpe_0178 | Natpe_0177 | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC. | 0.569 |
| AGB30120.1 | AGB30121.1 | Natpe_0178 | Natpe_0179 | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.618 |
| AGB30120.1 | AGB30122.1 | Natpe_0178 | Natpe_0180 | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.896 |
| AGB30121.1 | AGB30119.1 | Natpe_0179 | Natpe_0177 | TIGRFAM: phosphoesterase, MJ0936 family. | PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC. | 0.440 |
| AGB30121.1 | AGB30120.1 | Natpe_0179 | Natpe_0178 | TIGRFAM: phosphoesterase, MJ0936 family. | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | 0.618 |
| AGB30121.1 | AGB30122.1 | Natpe_0179 | Natpe_0180 | TIGRFAM: phosphoesterase, MJ0936 family. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.690 |
| AGB30121.1 | AGB30604.1 | Natpe_0179 | Natpe_0680 | TIGRFAM: phosphoesterase, MJ0936 family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.544 |
| AGB30121.1 | AGB33438.1 | Natpe_0179 | Natpe_3674 | TIGRFAM: phosphoesterase, MJ0936 family. | Putative ATPase involved in replication control, Cdc46/Mcm family; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region. | 0.763 |
| AGB30121.1 | purD | Natpe_0179 | Natpe_2498 | TIGRFAM: phosphoesterase, MJ0936 family. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.610 |
| AGB30122.1 | AGB30120.1 | Natpe_0180 | Natpe_0178 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Serine/threonine protein kinase involved in cell cycle control; PFAM: RIO1 family. | 0.896 |
| AGB30122.1 | AGB30121.1 | Natpe_0180 | Natpe_0179 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.690 |
| AGB30122.1 | AGB33438.1 | Natpe_0180 | Natpe_3674 | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | Putative ATPase involved in replication control, Cdc46/Mcm family; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region. | 0.568 |
| AGB30604.1 | AGB30121.1 | Natpe_0680 | Natpe_0179 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.544 |
| AGB33438.1 | AGB30121.1 | Natpe_3674 | Natpe_0179 | Putative ATPase involved in replication control, Cdc46/Mcm family; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.763 |
| AGB33438.1 | AGB30122.1 | Natpe_3674 | Natpe_0180 | Putative ATPase involved in replication control, Cdc46/Mcm family; PFAM: Helix-turn-helix; MCM2/3/5 family; TIGRFAM: intein N-terminal splicing region; intein C-terminal splicing region. | PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. | 0.568 |
| purD | AGB30121.1 | Natpe_2498 | Natpe_0179 | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | TIGRFAM: phosphoesterase, MJ0936 family. | 0.610 |