Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fau-1Protein of unknown function (DUF402); Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (478 aa)    
Predicted Functional Partners:
AGB30340.1
Hypothetical protein.
       0.919
AGB30338.1
Putative membrane protein.
 
     0.765
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.763
AGB30462.1
Putative DHD superfamily phosphohydrolase.
  
     0.703
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.703
AGB30323.1
SAM-dependent methyltransferase, tRNA(uracil-5)-methyltransferase; PFAM: TRAM domain.
  
     0.625
AGB32623.1
Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase.
  
     0.613
AGB33562.1
Thioredoxin-like protein; PFAM: NifU-like domain.
 
    0.576
AGB33425.1
ABC-type Fe3+-hydroxamate transport system, periplasmic component; PFAM: Periplasmic binding protein.
  
     0.563
AGB33113.1
PFAM: Acetyltransferase (GNAT) family.
 
     0.561
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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