| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30600.1 | AGB32788.1 | Natpe_0676 | Natpe_2993 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | 0.507 |
| AGB30600.1 | eif2g | Natpe_0676 | Natpe_0546 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.964 |
| AGB30600.1 | rps15p | Natpe_0676 | Natpe_2762 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15. | 0.938 |
| AGB30600.1 | rps3p | Natpe_0676 | Natpe_0876 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein S3, eukaryotic/archaeal type; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.449 |
| AGB30600.1 | rps5p | Natpe_0676 | Natpe_0890 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein S5/S2; With S4 and S12 plays an important role in translational accuracy. | 0.426 |
| AGB30600.1 | rps6e | Natpe_0676 | Natpe_0529 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.946 |
| AGB32788.1 | AGB30600.1 | Natpe_2993 | Natpe_0676 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.507 |
| AGB32788.1 | eif1a | Natpe_2993 | Natpe_0107 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.978 |
| AGB32788.1 | eif2b | Natpe_2993 | Natpe_1100 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.996 |
| AGB32788.1 | eif2g | Natpe_2993 | Natpe_0546 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.990 |
| AGB32788.1 | rpl7ae | Natpe_2993 | Natpe_1708 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. | 0.948 |
| AGB32788.1 | rps15p | Natpe_2993 | Natpe_2762 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15. | 0.959 |
| AGB32788.1 | rps3p | Natpe_2993 | Natpe_0876 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Ribosomal protein S3, eukaryotic/archaeal type; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.987 |
| AGB32788.1 | rps4e | Natpe_2993 | Natpe_0882 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | PFAM: Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family. | 0.962 |
| AGB32788.1 | rps5p | Natpe_2993 | Natpe_0890 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | Ribosomal protein S5/S2; With S4 and S12 plays an important role in translational accuracy. | 0.980 |
| AGB32788.1 | rps6e | Natpe_2993 | Natpe_0529 | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.979 |
| eif1a | AGB32788.1 | Natpe_0107 | Natpe_2993 | Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | 0.978 |
| eif1a | eif2b | Natpe_0107 | Natpe_1100 | Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.977 |
| eif1a | eif2g | Natpe_0107 | Natpe_0546 | Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.964 |
| eif1a | rpl7ae | Natpe_0107 | Natpe_1708 | Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. | 0.959 |