| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB29982.1 | AGB30600.1 | Natpe_0031 | Natpe_0676 | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein. | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.973 |
| AGB29982.1 | AGB30604.1 | Natpe_0031 | Natpe_0680 | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.477 |
| AGB30475.1 | AGB30600.1 | Natpe_0548 | Natpe_0676 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.940 |
| AGB30475.1 | AGB30604.1 | Natpe_0548 | Natpe_0680 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.503 |
| AGB30475.1 | eif2g | Natpe_0548 | Natpe_0546 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.956 |
| AGB30475.1 | rps15p | Natpe_0548 | Natpe_2762 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15. | 0.468 |
| AGB30475.1 | rps24e | Natpe_0548 | Natpe_0674 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.749 |
| AGB30475.1 | rps27ae | Natpe_0548 | Natpe_0675 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.511 |
| AGB30475.1 | rps6e | Natpe_0548 | Natpe_0529 | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.639 |
| AGB30600.1 | AGB29982.1 | Natpe_0676 | Natpe_0031 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein. | 0.973 |
| AGB30600.1 | AGB30475.1 | Natpe_0676 | Natpe_0548 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. | 0.940 |
| AGB30600.1 | AGB30601.1 | Natpe_0676 | Natpe_0677 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Hypothetical protein. | 0.956 |
| AGB30600.1 | AGB30604.1 | Natpe_0676 | Natpe_0680 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.945 |
| AGB30600.1 | AGB33594.1 | Natpe_0676 | Natpe_3834 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Kinase binding protein CGI-121. | 0.984 |
| AGB30600.1 | eif2g | Natpe_0676 | Natpe_0546 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.964 |
| AGB30600.1 | rps15p | Natpe_0676 | Natpe_2762 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15. | 0.938 |
| AGB30600.1 | rps24e | Natpe_0676 | Natpe_0674 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.981 |
| AGB30600.1 | rps27ae | Natpe_0676 | Natpe_0675 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.952 |
| AGB30600.1 | rps6e | Natpe_0676 | Natpe_0529 | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.946 |
| AGB30601.1 | AGB30600.1 | Natpe_0677 | Natpe_0676 | Hypothetical protein. | Metallohydrolase, glycoprotease/Kae1 family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. | 0.956 |
