STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT. (310 aa)    
Predicted Functional Partners:
AGB30780.1
Hypothetical protein.
       0.919
AGB30782.1
PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family.
       0.821
AGB31897.1
beta-RFAP synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
   
 0.799
AGB32062.1
Triphosphoribosyl-dephospho-CoA synthetase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.780
mer
Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT.
  
   
 0.677
AGB30496.1
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component; PFAM: NMT1/THI5 like.
 
     0.537
AGB32268.1
Hypothetical protein.
  
     0.505
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II.
      
 0.501
AGB32258.1
acyl-CoA synthetase (NDP forming); PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
      
 0.489
folD
5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
      
 0.489
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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