secY protein (Natrinema pellirubrum) - STRING interaction network

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secY

Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (486 aa)

Predicted Functional Partners:

rpl6p

0.993

rpl22p

0.992

rpl32e

0.992

rps19p

0.989

rpl19e

0.988

rpl30p

0.988

rpl4lp

0.987

rpl23

0.987

rps4e

0.987

rps8p

0.987

Your Current Organism:

Natrinema pellirubrum

NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpl19e	rpl22p	Natpe_0888	Natpe_0875	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rpl19e	rpl23	Natpe_0888	Natpe_0872	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Archaeal ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.999
rpl19e	rpl30p	Natpe_0888	Natpe_0891	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal.	0.999
rpl19e	rpl32e	Natpe_0888	Natpe_0887	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	PFAM: Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family.	0.999
rpl19e	rpl4lp	Natpe_0888	Natpe_0871	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.	0.999
rpl19e	rpl6p	Natpe_0888	Natpe_0886	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Archaeal ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rpl19e	rps19p	Natpe_0888	Natpe_0874	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Ribosomal protein S19/S15; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpl19e	rps4e	Natpe_0888	Natpe_0882	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	PFAM: Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
rpl19e	rps8p	Natpe_0888	Natpe_0885	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.	0.999
rpl19e	secY	Natpe_0888	Natpe_0893	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.988
rpl22p	rpl19e	Natpe_0875	Natpe_0888	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl22p	rpl23	Natpe_0875	Natpe_0872	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Archaeal ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.999
rpl22p	rpl30p	Natpe_0875	Natpe_0891	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal.	0.999
rpl22p	rpl32e	Natpe_0875	Natpe_0887	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	PFAM: Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family.	0.999
rpl22p	rpl4lp	Natpe_0875	Natpe_0871	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.	0.999
rpl22p	rpl6p	Natpe_0875	Natpe_0886	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Archaeal ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rpl22p	rps19p	Natpe_0875	Natpe_0874	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Ribosomal protein S19/S15; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpl22p	rps4e	Natpe_0875	Natpe_0882	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	PFAM: Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
rpl22p	rps8p	Natpe_0875	Natpe_0885	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.	0.999
rpl22p	secY	Natpe_0875	Natpe_0893	Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.992

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