| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30367.1 | AGB30521.1 | Natpe_0437 | Natpe_0595 | Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase. | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | 0.620 |
| AGB30367.1 | AGB30860.1 | Natpe_0437 | Natpe_0946 | Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase. | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.551 |
| AGB30521.1 | AGB30367.1 | Natpe_0595 | Natpe_0437 | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase. | 0.620 |
| AGB30521.1 | AGB30860.1 | Natpe_0595 | Natpe_0946 | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.711 |
| AGB30521.1 | AGB31404.1 | Natpe_0595 | Natpe_1502 | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.654 |
| AGB30860.1 | AGB30367.1 | Natpe_0946 | Natpe_0437 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; Chlorite dismutase. | 0.551 |
| AGB30860.1 | AGB30521.1 | Natpe_0946 | Natpe_0595 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | 0.711 |
| AGB30860.1 | AGB30861.1 | Natpe_0946 | Natpe_0947 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: HTH DNA binding domain. | 0.565 |
| AGB30860.1 | AGB31048.1 | Natpe_0946 | Natpe_1136 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Flavin-dependent dehydrogenase; PFAM: FAD binding domain. | 0.507 |
| AGB30860.1 | AGB31404.1 | Natpe_0946 | Natpe_1502 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.806 |
| AGB30860.1 | carS | Natpe_0946 | Natpe_0776 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.595 |
| AGB30860.1 | egsA | Natpe_0946 | Natpe_0479 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Glycerol dehydrogenase-like oxidoreductase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | 0.949 |
| AGB30860.1 | gatC | Natpe_0946 | Natpe_2362 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.513 |
| AGB30860.1 | topA | Natpe_0946 | Natpe_2833 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.656 |
| AGB30860.1 | ubiA | Natpe_0946 | Natpe_2728 | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.978 |
| AGB30861.1 | AGB30860.1 | Natpe_0947 | Natpe_0946 | PFAM: HTH DNA binding domain. | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.565 |
| AGB31048.1 | AGB30860.1 | Natpe_1136 | Natpe_0946 | Flavin-dependent dehydrogenase; PFAM: FAD binding domain. | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.507 |
| AGB31048.1 | ubiA | Natpe_1136 | Natpe_2728 | Flavin-dependent dehydrogenase; PFAM: FAD binding domain. | 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.568 |
| AGB31404.1 | AGB30521.1 | Natpe_1502 | Natpe_0595 | Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Putative membrane protein; PFAM: Protein of unknown function (DUF1405). | 0.654 |
| AGB31404.1 | AGB30860.1 | Natpe_1502 | Natpe_0946 | Serine acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.806 |