STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AGB30862.1NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family. (269 aa)    
Predicted Functional Partners:
AGB32993.1
PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain.
   
 
  0.962
AGB30272.1
NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase.
 
  
 0.927
AGB32589.1
Putative sugar kinase; PFAM: ATP-NAD kinase.
  
 
 0.922
nadK
Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.922
AGB32537.1
NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase.
    
 0.918
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.918
AGB30162.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme.
    
 0.814
AGB33213.1
Deacetylase, histone deacetylase/acetoin utilization protein; PFAM: Histone deacetylase domain.
   
 0.802
AGB33243.1
PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
    
 0.798
AGB32165.1
DnaJ-class molecular chaperone with C-terminal Zn finger domain; PFAM: DnaJ domain.
   
 0.700
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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