Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trm1N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (371 aa)    
Predicted Functional Partners:
AGB31981.1
rRNA biogenesis protein; PFAM: Putative snoRNA binding domain.
 
    0.848
AGB30953.1
Putative metal-binding protein.
       0.835
truB
rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.790
AGB30956.1
Putative membrane protein; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN).
       0.764
AGB30122.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein.
  
    0.755
AGB30056.1
PFAM: Putative RNA methylase family UPF0020; TIGRFAM: TIGR01177 family protein.
  
 
 0.746
pus10
TIGR01213 family protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
  
   
 0.745
rpoD
DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
 
   0.730
AGB31273.1
PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain.
 
   0.727
rpl24p
Ribosomal protein L24p/L26e, archaeal/eukaryotic; Located at the polypeptide exit tunnel on the outside of the subunit.
  
 
   0.716
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
Server load: low (18%) [HD]