STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB30985.1PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. (133 aa)    
Predicted Functional Partners:
msrA
methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
AGB31767.1
PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase.
 
 0.984
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
   
 
 0.665
AGB31104.1
Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutaredoxin; TIGRFAM: thioredoxin-disulfide reductase; Glutaredoxin, GrxC family.
  
  
 0.664
AGB30210.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin.
   
 0.528
AGB31024.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin.
   
 0.528
AGB31359.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin.
   
 0.528
AGB31381.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin.
   
 0.528
AGB32213.1
Peroxiredoxin; PFAM: AhpC/TSA family.
   
 0.528
AGB32302.1
PFAM: Thioredoxin.
   
 0.528
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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