| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30970.1 | AGB31336.1 | Natpe_1058 | Natpe_1433 | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.443 |
| AGB30970.1 | mptA | Natpe_1058 | Natpe_3511 | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.818 |
| AGB30970.1 | pyrC | Natpe_1058 | Natpe_1331 | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.564 |
| AGB31336.1 | AGB30970.1 | Natpe_1433 | Natpe_1058 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | 0.443 |
| AGB31336.1 | AGB31337.1 | Natpe_1433 | Natpe_1434 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Hypothetical protein. | 0.420 |
| AGB31336.1 | AGB31338.1 | Natpe_1433 | Natpe_1435 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Putative hydrolase (metallo-beta-lactamase superfamily); PFAM: Metallo-beta-lactamase superfamily. | 0.447 |
| AGB31336.1 | AGB33415.1 | Natpe_1433 | Natpe_3650 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | PFAM: Carbonic anhydrase. | 0.652 |
| AGB31336.1 | mptA | Natpe_1433 | Natpe_3511 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.420 |
| AGB31336.1 | pyrC | Natpe_1433 | Natpe_1331 | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.543 |
| AGB31337.1 | AGB31336.1 | Natpe_1434 | Natpe_1433 | Hypothetical protein. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.420 |
| AGB31337.1 | AGB31338.1 | Natpe_1434 | Natpe_1435 | Hypothetical protein. | Putative hydrolase (metallo-beta-lactamase superfamily); PFAM: Metallo-beta-lactamase superfamily. | 0.865 |
| AGB31338.1 | AGB31336.1 | Natpe_1435 | Natpe_1433 | Putative hydrolase (metallo-beta-lactamase superfamily); PFAM: Metallo-beta-lactamase superfamily. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.447 |
| AGB31338.1 | AGB31337.1 | Natpe_1435 | Natpe_1434 | Putative hydrolase (metallo-beta-lactamase superfamily); PFAM: Metallo-beta-lactamase superfamily. | Hypothetical protein. | 0.865 |
| AGB33415.1 | AGB31336.1 | Natpe_3650 | Natpe_1433 | PFAM: Carbonic anhydrase. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.652 |
| mptA | AGB30970.1 | Natpe_3511 | Natpe_1058 | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | 0.818 |
| mptA | AGB31336.1 | Natpe_3511 | Natpe_1433 | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.420 |
| mptA | pyrC | Natpe_3511 | Natpe_1331 | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.441 |
| pyrC | AGB30970.1 | Natpe_1331 | Natpe_1058 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Putative GTPase, G3E family; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain. | 0.564 |
| pyrC | AGB31336.1 | Natpe_1331 | Natpe_1433 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.543 |
| pyrC | mptA | Natpe_1331 | Natpe_3511 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.441 |