Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB31470.1Subtilisin-like serine protease; PFAM: Subtilase family. (557 aa)    
Predicted Functional Partners:
AGB31469.1
Subtilisin-like serine protease; PFAM: Subtilase family.
 
  
0.943
dnaK
Chaperone protein DnaK; Acts as a chaperone.
  
 
 0.824
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
  
 0.761
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
     
 0.747
AGB31097.1
Subtilisin-like serine protease; PFAM: Subtilase family; Belongs to the peptidase S8 family.
  
 
  
0.709
AGB30813.1
Subtilisin-like serine protease; PFAM: Subtilase family; Belongs to the peptidase S8 family.
  
 
  
0.704
AGB31471.1
PFAM: Protein of unknown function DUF88; TIGRFAM: TIGR00288 family protein.
       0.409
AGB30412.1
Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family.
  
 
 0.405
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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