| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB29987.1 | AGB31581.1 | Natpe_0036 | Natpe_1687 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | 0.496 |
| AGB29987.1 | hisA | Natpe_0036 | Natpe_0057 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.510 |
| AGB29987.1 | hisF | Natpe_0036 | Natpe_2340 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.505 |
| AGB30934.1 | AGB31581.1 | Natpe_1022 | Natpe_1687 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | 0.513 |
| AGB30934.1 | hisA | Natpe_1022 | Natpe_0057 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.518 |
| AGB30934.1 | hisF | Natpe_1022 | Natpe_2340 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.546 |
| AGB31389.1 | AGB31581.1 | Natpe_1487 | Natpe_1687 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | 0.496 |
| AGB31389.1 | hisA | Natpe_1487 | Natpe_0057 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.510 |
| AGB31389.1 | hisF | Natpe_1487 | Natpe_2340 | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.505 |
| AGB31578.1 | AGB31579.1 | Natpe_1684 | Natpe_1685 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | 0.598 |
| AGB31578.1 | AGB31581.1 | Natpe_1684 | Natpe_1687 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | 0.590 |
| AGB31578.1 | AGB31583.1 | Natpe_1684 | Natpe_1689 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.595 |
| AGB31578.1 | mvk | Natpe_1684 | Natpe_1688 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.538 |
| AGB31578.1 | phnC | Natpe_1684 | Natpe_1686 | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | ABC-type phosphate/phosphonate transport system, ATPase component; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. | 0.598 |
| AGB31579.1 | AGB31578.1 | Natpe_1685 | Natpe_1684 | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. | 0.598 |
| AGB31579.1 | AGB31581.1 | Natpe_1685 | Natpe_1687 | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | 0.996 |
| AGB31579.1 | AGB31583.1 | Natpe_1685 | Natpe_1689 | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.524 |
| AGB31579.1 | mvk | Natpe_1685 | Natpe_1688 | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.524 |
| AGB31579.1 | phnC | Natpe_1685 | Natpe_1686 | PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphonate ABC transporter, permease protein PhnE. | ABC-type phosphate/phosphonate transport system, ATPase component; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. | 0.996 |
| AGB31581.1 | AGB29987.1 | Natpe_1687 | Natpe_0036 | ABC-type phosphate/phosphonate transport system, periplasmic component; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein. | Phosphate/sulfate permease; PFAM: Phosphate transporter family. | 0.496 |