| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30052.1 | AGB30587.1 | Natpe_0109 | Natpe_0662 | PFAM: Protein of unknown function (DUF460). | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | 0.535 |
| AGB30052.1 | AGB31680.1 | Natpe_0109 | Natpe_1793 | PFAM: Protein of unknown function (DUF460). | Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function. | 0.652 |
| AGB30052.1 | AGB31906.1 | Natpe_0109 | Natpe_2077 | PFAM: Protein of unknown function (DUF460). | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | 0.528 |
| AGB30052.1 | AGB32060.1 | Natpe_0109 | Natpe_2235 | PFAM: Protein of unknown function (DUF460). | TIGRFAM: TIM-barrel protein, putative. | 0.571 |
| AGB30052.1 | AGB32785.1 | Natpe_0109 | Natpe_2990 | PFAM: Protein of unknown function (DUF460). | Putative transcriptional regulator. | 0.507 |
| AGB30052.1 | AGB33638.1 | Natpe_0109 | Natpe_3879 | PFAM: Protein of unknown function (DUF460). | PFAM: Uncharacterized protein conserved in archaea (DUF2073). | 0.696 |
| AGB30052.1 | cofC | Natpe_0109 | Natpe_3127 | PFAM: Protein of unknown function (DUF460). | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.685 |
| AGB30052.1 | ef1B | Natpe_0109 | Natpe_1410 | PFAM: Protein of unknown function (DUF460). | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.493 |
| AGB30052.1 | tfe | Natpe_0109 | Natpe_2668 | PFAM: Protein of unknown function (DUF460). | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.691 |
| AGB30587.1 | AGB30052.1 | Natpe_0662 | Natpe_0109 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | PFAM: Protein of unknown function (DUF460). | 0.535 |
| AGB30587.1 | AGB31680.1 | Natpe_0662 | Natpe_1793 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function. | 0.692 |
| AGB30587.1 | AGB31906.1 | Natpe_0662 | Natpe_2077 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | 0.620 |
| AGB30587.1 | AGB32060.1 | Natpe_0662 | Natpe_2235 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | TIGRFAM: TIM-barrel protein, putative. | 0.619 |
| AGB30587.1 | AGB32785.1 | Natpe_0662 | Natpe_2990 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | Putative transcriptional regulator. | 0.688 |
| AGB30587.1 | AGB33638.1 | Natpe_0662 | Natpe_3879 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | PFAM: Uncharacterized protein conserved in archaea (DUF2073). | 0.730 |
| AGB30587.1 | cofC | Natpe_0662 | Natpe_3127 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.724 |
| AGB30587.1 | ef1B | Natpe_0662 | Natpe_1410 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. | 0.546 |
| AGB30587.1 | rnp3 | Natpe_0662 | Natpe_2515 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | RNase P/RNase MRP subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. | 0.680 |
| AGB30587.1 | tfe | Natpe_0662 | Natpe_2668 | ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.506 |
| AGB31680.1 | AGB30052.1 | Natpe_1793 | Natpe_0109 | Putative transcriptional regulator, contains C-terminal CBS domains; PFAM: Domain of unknown function. | PFAM: Protein of unknown function (DUF460). | 0.652 |