| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB29976.1 | AGB32109.1 | Natpe_0025 | Natpe_2289 | Fe-S oxidoreductase; PFAM: Cysteine-rich domain; 4Fe-4S binding domain. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.469 |
| AGB31325.1 | AGB32109.1 | Natpe_1421 | Natpe_2289 | HemK-related putative methylase; PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.458 |
| AGB31325.1 | rnhB | Natpe_1421 | Natpe_3198 | HemK-related putative methylase; PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase. | Ribonuclease H, mammalian HI/archaeal HII subfamily; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.411 |
| AGB31325.1 | rpl21e | Natpe_1421 | Natpe_1418 | HemK-related putative methylase; PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase. | PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.662 |
| AGB32105.1 | AGB32109.1 | Natpe_2285 | Natpe_2289 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.479 |
| AGB32105.1 | mptE | Natpe_2285 | Natpe_2284 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.980 |
| AGB32109.1 | AGB29976.1 | Natpe_2289 | Natpe_0025 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Fe-S oxidoreductase; PFAM: Cysteine-rich domain; 4Fe-4S binding domain. | 0.469 |
| AGB32109.1 | AGB31325.1 | Natpe_2289 | Natpe_1421 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | HemK-related putative methylase; PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase. | 0.458 |
| AGB32109.1 | AGB32105.1 | Natpe_2289 | Natpe_2285 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.479 |
| AGB32109.1 | AGB32110.1 | Natpe_2289 | Natpe_2290 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Hypothetical protein. | 0.637 |
| AGB32109.1 | AGB32290.1 | Natpe_2289 | Natpe_2476 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase. | 0.522 |
| AGB32109.1 | AGB33563.1 | Natpe_2289 | Natpe_3803 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.494 |
| AGB32109.1 | mptE | Natpe_2289 | Natpe_2284 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.522 |
| AGB32109.1 | rnhB | Natpe_2289 | Natpe_3198 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Ribonuclease H, mammalian HI/archaeal HII subfamily; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.548 |
| AGB32109.1 | rpl21e | Natpe_2289 | Natpe_1418 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.486 |
| AGB32109.1 | rrmJ | Natpe_2289 | Natpe_0141 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.597 |
| AGB32110.1 | AGB32109.1 | Natpe_2290 | Natpe_2289 | Hypothetical protein. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.637 |
| AGB32290.1 | AGB32109.1 | Natpe_2476 | Natpe_2289 | PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.522 |
| AGB32290.1 | rpl21e | Natpe_2476 | Natpe_1418 | PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase. | PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. | 0.512 |
| AGB33563.1 | AGB32109.1 | Natpe_3803 | Natpe_2289 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.494 |