STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AGB32623.1Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. (299 aa)    
Predicted Functional Partners:
AGB32624.1
Methylase involved in ubiquinone/menaquinone biosynthesis.
       0.871
AGB32622.1
Putative membrane protein; PFAM: Protein of unknown function (DUF420).
 
     0.653
fau-1
Protein of unknown function (DUF402); Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
  
     0.613
AGB31963.1
ATP-grasp superfamily enzyme; PFAM: PAC2 family.
  
     0.608
AGB31530.1
Hypothetical protein; PFAM: Domain of unknown function (DUF371).
  
     0.551
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
     0.546
AGB31311.1
Hypothetical protein; Involved in DNA damage repair.
  
     0.534
AGB32625.1
Hypothetical protein.
       0.514
AGB32683.1
Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain.
  
     0.509
thi4
Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
 
   
 0.487
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.