| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB31104.1 | AGB33001.1 | Natpe_1198 | Natpe_3211 | Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutaredoxin; TIGRFAM: thioredoxin-disulfide reductase; Glutaredoxin, GrxC family. | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | 0.507 |
| AGB31104.1 | queE | Natpe_1198 | Natpe_2893 | Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutaredoxin; TIGRFAM: thioredoxin-disulfide reductase; Glutaredoxin, GrxC family. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.471 |
| AGB32688.1 | AGB32689.1 | Natpe_2891 | Natpe_2892 | Hypothetical protein. | PFAM: 6-pyruvoyl tetrahydropterin synthase. | 0.688 |
| AGB32688.1 | queC | Natpe_2891 | Natpe_2894 | Hypothetical protein. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.560 |
| AGB32688.1 | queE | Natpe_2891 | Natpe_2893 | Hypothetical protein. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.688 |
| AGB32689.1 | AGB32688.1 | Natpe_2892 | Natpe_2891 | PFAM: 6-pyruvoyl tetrahydropterin synthase. | Hypothetical protein. | 0.688 |
| AGB32689.1 | dcd | Natpe_2892 | Natpe_1047 | PFAM: 6-pyruvoyl tetrahydropterin synthase. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.541 |
| AGB32689.1 | queC | Natpe_2892 | Natpe_2894 | PFAM: 6-pyruvoyl tetrahydropterin synthase. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.992 |
| AGB32689.1 | queE | Natpe_2892 | Natpe_2893 | PFAM: 6-pyruvoyl tetrahydropterin synthase. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| AGB32689.1 | tgtA | Natpe_2892 | Natpe_3147 | PFAM: 6-pyruvoyl tetrahydropterin synthase. | tRNA-guanine transglycosylase, archaeosine-15-forming; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.453 |
| AGB33001.1 | AGB31104.1 | Natpe_3211 | Natpe_1198 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Glutaredoxin; TIGRFAM: thioredoxin-disulfide reductase; Glutaredoxin, GrxC family. | 0.507 |
| AGB33001.1 | dcd | Natpe_3211 | Natpe_1047 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.460 |
| AGB33001.1 | pyrF | Natpe_3211 | Natpe_0853 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.931 |
| AGB33001.1 | queE | Natpe_3211 | Natpe_2893 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.581 |
| AGB33001.1 | tmk | Natpe_3211 | Natpe_3124 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | 0.662 |
| dcd | AGB32689.1 | Natpe_1047 | Natpe_2892 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | PFAM: 6-pyruvoyl tetrahydropterin synthase. | 0.541 |
| dcd | AGB33001.1 | Natpe_1047 | Natpe_3211 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | 0.460 |
| dcd | queC | Natpe_1047 | Natpe_2894 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.482 |
| dcd | queE | Natpe_1047 | Natpe_2893 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.541 |
| dcd | tmk | Natpe_1047 | Natpe_3124 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | 0.686 |