| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB31641.1 | AGB32713.1 | Natpe_1752 | Natpe_2916 | Putative sugar phosphatase of HAD superfamily; PFAM: NUDIX domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA; manually curated. | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | 0.549 |
| AGB32544.1 | AGB32713.1 | Natpe_2742 | Natpe_2916 | Membrane-associated phospholipid phosphatase; PFAM: PAP2 superfamily. | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | 0.551 |
| AGB32711.1 | AGB32713.1 | Natpe_2914 | Natpe_2916 | PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family. | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | 0.499 |
| AGB32713.1 | AGB31641.1 | Natpe_2916 | Natpe_1752 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | Putative sugar phosphatase of HAD superfamily; PFAM: NUDIX domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA; manually curated. | 0.549 |
| AGB32713.1 | AGB32544.1 | Natpe_2916 | Natpe_2742 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | Membrane-associated phospholipid phosphatase; PFAM: PAP2 superfamily. | 0.551 |
| AGB32713.1 | AGB32711.1 | Natpe_2916 | Natpe_2914 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family. | 0.499 |
| AGB32713.1 | hisB | Natpe_2916 | Natpe_0055 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | PFAM: Imidazoleglycerol-phosphate dehydratase. | 0.714 |
| AGB32713.1 | hisC | Natpe_2916 | Natpe_2228 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase. | 0.932 |
| AGB32713.1 | hisD | Natpe_2916 | Natpe_2260 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.947 |
| AGB32713.1 | hisE | Natpe_2916 | Natpe_0270 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.595 |
| AGB32713.1 | hisF | Natpe_2916 | Natpe_2340 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.577 |
| AGB32713.1 | hisG | Natpe_2916 | Natpe_0117 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.531 |
| AGB32713.1 | hisI | Natpe_2916 | Natpe_0085 | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.709 |
| hisB | AGB32713.1 | Natpe_0055 | Natpe_2916 | PFAM: Imidazoleglycerol-phosphate dehydratase. | PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase, HisJ family. | 0.714 |
| hisB | hisC | Natpe_0055 | Natpe_2228 | PFAM: Imidazoleglycerol-phosphate dehydratase. | PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase. | 0.999 |
| hisB | hisD | Natpe_0055 | Natpe_2260 | PFAM: Imidazoleglycerol-phosphate dehydratase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.998 |
| hisB | hisE | Natpe_0055 | Natpe_0270 | PFAM: Imidazoleglycerol-phosphate dehydratase. | PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.948 |
| hisB | hisF | Natpe_0055 | Natpe_2340 | PFAM: Imidazoleglycerol-phosphate dehydratase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.998 |
| hisB | hisG | Natpe_0055 | Natpe_0117 | PFAM: Imidazoleglycerol-phosphate dehydratase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.996 |
| hisB | hisI | Natpe_0055 | Natpe_0085 | PFAM: Imidazoleglycerol-phosphate dehydratase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.980 |