Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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cofC2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (223 aa)    
Predicted Functional Partners:
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
  
 0.978
cofG
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
   
 0.960
cetZ-2
Cell division GTPase; Involved in cell shape control; Belongs to the CetZ family.
 
   
 0.836
AGB32925.1
Thiamine biosynthesis protein ThiH-like enzyme; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily.
 
   
 0.819
tmk
PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase.
     
 0.781
AGB30386.1
Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain.
       0.762
AGB32060.1
TIGRFAM: TIM-barrel protein, putative.
 
     0.749
AGB33638.1
PFAM: Uncharacterized protein conserved in archaea (DUF2073).
  
     0.744
cofE
F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
 
   
 0.736
AGB31906.1
RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain.
  
     0.733
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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