| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB30320.1 | AGB30988.1 | Natpe_0389 | Natpe_1076 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | 0.916 |
| AGB30320.1 | AGB31478.1 | Natpe_0389 | Natpe_1579 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | 0.531 |
| AGB30320.1 | AGB31583.1 | Natpe_0389 | Natpe_1689 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.906 |
| AGB30320.1 | AGB31591.1 | Natpe_0389 | Natpe_1697 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |
| AGB30320.1 | AGB32587.1 | Natpe_0389 | Natpe_2785 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |
| AGB30320.1 | AGB32592.1 | Natpe_0389 | Natpe_2790 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.521 |
| AGB30320.1 | AGB33141.1 | Natpe_0389 | Natpe_3354 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 0.925 |
| AGB30320.1 | AGB33236.1 | Natpe_0389 | Natpe_3461 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.476 |
| AGB30320.1 | fni | Natpe_0389 | Natpe_1301 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.927 |
| AGB30988.1 | AGB30320.1 | Natpe_1076 | Natpe_0389 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |
| AGB30988.1 | AGB31478.1 | Natpe_1076 | Natpe_1579 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | 0.588 |
| AGB30988.1 | AGB31591.1 | Natpe_1076 | Natpe_1697 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.949 |
| AGB30988.1 | AGB32587.1 | Natpe_1076 | Natpe_2785 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.949 |
| AGB30988.1 | AGB32592.1 | Natpe_1076 | Natpe_2790 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.471 |
| AGB30988.1 | AGB33141.1 | Natpe_1076 | Natpe_3354 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 0.802 |
| AGB30988.1 | AGB33236.1 | Natpe_1076 | Natpe_3461 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.484 |
| AGB30988.1 | fni | Natpe_1076 | Natpe_1301 | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.410 |
| AGB31478.1 | AGB30320.1 | Natpe_1579 | Natpe_0389 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.531 |
| AGB31478.1 | AGB30988.1 | Natpe_1579 | Natpe_1076 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | Phytoene/squalene synthetase; PFAM: Squalene/phytoene synthase. | 0.588 |
| AGB31478.1 | AGB31583.1 | Natpe_1579 | Natpe_1689 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.589 |