STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemD-2PFAM: Uroporphyrinogen-III synthase HemD. (246 aa)    
Predicted Functional Partners:
AGB33552.1
PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
 
 0.998
AGB33553.1
uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase.
 
 0.996
AGB33545.1
PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.921
hemD
PFAM: Uroporphyrinogen-III synthase HemD.
  
  
 
0.903
AGB33555.1
Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); PFAM: Bacterial capsule synthesis protein PGA_cap.
       0.773
AGB33556.1
Single-stranded DNA-specific exonuclease; PFAM: DHH family; DHHA1 domain.
 
     0.710
AGB30502.1
TIGRFAM: siroheme synthase, N-terminal domain.
 
  
 0.598
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.582
hemA-2
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.555
AGB33551.1
Truncated hemoglobin; PFAM: Bacterial-like globin.
  
  
 0.544
Your Current Organism:
Natrinema pellirubrum
NCBI taxonomy Id: 797303
Other names: N. pellirubrum DSM 15624, Natrinema pellirubrum DSM 15624, Natrinema pellirubrum JCM 10476, Natrinema pellirubrum NCIMB 786, Natrinema pellirubrum str. DSM 15624, Natrinema pellirubrum strain DSM 15624
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