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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ71368.1TIGRFAM: siroheme synthase, N-terminal domain. (207 aa)    
Predicted Functional Partners:
AFZ71367.1
uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.998
AFZ71370.1
Precorrin-2 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.978
AFZ71371.1
Precorrin-4 methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase.
 
   
 0.896
AFZ71530.1
PAPS reductase/FAD synthetase family protein; PFAM: Phosphoadenosine phosphosulfate reductase family.
  
  
 0.778
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
   
 0.775
AFZ72579.1
Putative kinase; PFAM: Chromatin associated protein KTI12.
  
  
 0.768
AFZ71372.1
Cobalamin biosynthesis protein CbiG; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal.
 
   
 0.762
AFZ71373.1
precorrin-3B methylase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase.
 
   
 0.759
hemD
PFAM: Uroporphyrinogen-III synthase HemD.
 
  
 0.740
hemC
PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
 
  
 0.724
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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