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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutGFormimidoylglutamase; PFAM: Arginase family; TIGRFAM: formimidoylglutamase; Belongs to the arginase family. (346 aa)    
Predicted Functional Partners:
hutI
Imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.963
hutH
PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase.
 
  
 0.942
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.911
AFZ74700.1
PFAM: Spermine/spermidine synthase.
  
  
 0.730
AFZ74059.1
PFAM: Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; FAD dependent oxidoreductase.
 
  
 0.687
AFZ72820.1
PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.679
AFZ72436.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.573
AFZ71395.1
PFAM: HTH DNA binding domain.
       0.572
AFZ73819.1
Putative amidohydrolase; PFAM: Carbon-nitrogen hydrolase.
  
 0.524
nadK
Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.498
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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