close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ71454.1Trk-type K+ transport system, membrane component; PFAM: Cation transport protein. (505 aa)    
Predicted Functional Partners:
AFZ74281.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family.
 
 
 0.947
AFZ73281.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain.
 
 
 0.943
AFZ73830.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.900
AFZ73621.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.873
trkA
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.828
AFZ71453.1
Putative membrane protein.
 
     0.696
AFZ71452.1
rRNA biogenesis protein; PFAM: Putative snoRNA binding domain; BAAT / Acyl-CoA thioester hydrolase C terminal.
  
    0.672
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.651
AFZ71455.1
PFAM: Amino acid permease; Universal stress protein family.
   
 
 0.596
AFZ71450.1
WD40-like repeat protein; PFAM: PQQ enzyme repeat.
       0.531
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.