close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkAK+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain. (444 aa)    
Predicted Functional Partners:
AFZ71459.1
Trk-type K+ transport system, membrane component; PFAM: Cation transport protein.
 
   
 0.959
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.891
AFZ71454.1
Trk-type K+ transport system, membrane component; PFAM: Cation transport protein.
 
   
 0.828
AFZ74281.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family.
 
   
0.673
AFZ72672.1
Ammonia permease; PFAM: Ammonium Transporter Family; Nitrogen regulatory protein P-II; TIGRFAM: ammonium transporter; Belongs to the P(II) protein family.
  
  
 0.665
AFZ73281.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain.
 
   
0.663
AFZ71457.1
PFAM: Amino acid permease; Universal stress protein family.
     
 0.630
AFZ71456.1
Hypothetical protein.
       0.615
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
     
 0.508
AFZ72199.1
Hypothetical protein.
  
  
 0.493
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.