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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ71581.1PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, putative. (247 aa)    
Predicted Functional Partners:
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
     0.873
AFZ74884.1
PFAM: Protein of unknown function (DUF447).
 
     0.758
AFZ71675.1
RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain.
  
    0.743
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
 
     0.740
AFZ73898.1
RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: S1 RNA binding domain; OB-fold nucleic acid binding domain.
  
    0.738
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
 
 0.715
AFZ72094.1
Putative metal-binding protein; PFAM: Uncharacterised protein family UPF0058.
  
     0.697
AFZ74883.1
Triphosphoribosyl-dephospho-CoA synthetase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.676
rnp3
RNase P/RNase MRP subunit p30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
    0.673
AFZ71638.1
PFAM: Protein of unknown function (DUF555); Belongs to the UPF0212 family.
  
     0.666
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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