Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFZ71710.1Hypothetical protein. (273 aa)    
Predicted Functional Partners:
AFZ71709.1
ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter.
 
  
 0.988
AFZ71949.1
PFAM: Nitroreductase family; TIGRFAM: SagB-type dehydrogenase domain.
 
  
 0.693
AFZ73975.1
PFAM: YcaO-like family; TIGRFAM: uncharacterized domain; bacteriocin biosynthesis docking scaffold, SagD family.
  
  
 0.600
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.571
AFZ71711.1
Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase.
       0.556
AFZ74814.1
Putative ATP-grasp enzyme.
  
     0.539
AFZ72244.1
Putative metal-dependent membrane protease; PFAM: CAAX amino terminal protease family.
 
    0.533
AFZ73558.1
Putative lipoprotein involved in nitrous oxide reduction; PFAM: NosL.
  
     0.524
AFZ72331.1
PFAM: E3 Ubiquitin ligase.
  
     0.518
AFZ72581.1
Putative pyrophosphatase; PFAM: MazG nucleotide pyrophosphohydrolase domain.
 
     0.506
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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