STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ71812.1Hypothetical protein. (92 aa)    
Predicted Functional Partners:
AFZ72090.1
PFAM: Trm112p-like protein.
  
     0.675
AFZ73671.1
Putative transcriptional regulator with CopG/Arc/MetJ DNA-binding domain and metal-binding domain; PFAM: Ribbon-helix-helix protein, copG family.
  
    0.653
mre11
DNA repair exonuclease; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.
 
     0.652
AFZ72938.1
Leader peptidase family protein; PFAM: Archaeal Peptidase A24 C-terminus Type II; Type IV leader peptidase family.
  
   
 0.610
AFZ71599.1
Putative acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); Protein of unknown function, DUF583.
  
     0.606
rad50
ATPase involved in DNA repair; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily.
       0.602
AFZ74316.1
Putative transcriptional regulator.
  
     0.572
AFZ74820.1
PFAM: Uncharacterized protein conserved in archaea (DUF2150).
  
     0.561
AFZ73436.1
Hypothetical protein.
  
     0.542
AFZ71476.1
Hypothetical protein.
  
  
 0.541
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.