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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ71899.1Putative anaerobic dehydrogenase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type. (702 aa)    
Predicted Functional Partners:
AFZ71662.1
Fe-S-cluster-containing hydrogenase subunit; PFAM: 4Fe-4S binding domain.
  
 0.966
AFZ74001.1
Polyferredoxin, heterodixulfide reductase subunit A.
   
 0.942
AFZ74002.1
PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
  
 0.942
AFZ74004.1
Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 0.940
AFZ73305.1
NAD(P)H-nitrite reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
   
 0.918
AFZ74003.1
Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
    
 0.907
AFZ71664.1
PFAM: Prokaryotic cytochrome b561; TIGRFAM: formate dehydrogenase, gamma subunit.
    
 0.904
AFZ74056.1
Formate dehydrogenase, alpha subunit, archaeal-type; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type.
  
  
 
0.904
AFZ71795.1
NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
    
 0.883
AFZ71524.1
Fe-S-cluster-containing hydrogenase subunit.
  
 
 0.715
Your Current Organism:
Natronobacterium gregoryi
NCBI taxonomy Id: 797304
Other names: N. gregoryi SP2, Natronobacterium gregoryi ATCC 43098, Natronobacterium gregoryi JCM 8860, Natronobacterium gregoryi NCIMB 2189, Natronobacterium gregoryi SP2, Natronobacterium gregoryi str. SP2, Natronobacterium gregoryi strain SP2
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